Neuropathy refers to the disease or dysfunction of one or more peripheral nerves, typically causing numbness or weakness, especially in the arms, legs, hands or feet. The peripheral nervous system makes up the nerves outside of the brain and spinal cord that connect the central nervous system to sensory organs, such as the eye and ear, and to other organs of the body and muscles. Damage to these nerves can be caused by a variety of sources, including diabetes, chemo-therapy, inflammatory infections and more.